The Blues head into the game fresh from having sealed a 1-0 victory away to Tottenham Hotspur on Thursday night as Thomas Tuchel oversaw consecutive victories for the first time as Chelsea FC boss.
Chelsea FC will now be looking to string together a positive series of results as they look to climb the Premier League table and get themselves back into contention for a top-four finish in the top flight.
The west London side started the weekend in sixth place in the Premier League table as they bid to improve on the fourth-place finish they achieved under Frank Lampard the last term.
Werner is yet to score under new boss Tuchel, but former Liverpool FC and Manchester United star Owen are backing the German to help fire the Blues to victory over the Blades on Sunday.
Writing his column for BetVictor, Owen said: “It’s two wins and three clean sheets for Chelsea under new boss Thomas Tuchel.
“The Blues have certainly looked more solid since the German has arrived, with Thursday’s win at Tottenham testament to that. “They travel to the Steel City to take on a resurgent Sheffield United side. The Blades are putting in a late run to escape relegation, although they’ve probably left it too late.
“United have been impressive in recent weeks, however, Chelsea is growing in confidence and I think Tuchel may be the man to unlock the potential of fellow countryman Timo Werner.
“I reckon the German could notch here in an away win.”
Chelsea FC is in FA Cup action next week when they take on Barnsley in the fifth round away from home on Thursday night.
The Blues will then host Newcastle United in the Premier League on Monday 15 February.